Cell isolation

Why automate cell isolation

Manual cell isolation and enrichment methods can be time-consuming, imprecise, and prone to contamination. To address these concerns, choose automated and functionally closed technologies, such as Cytiva's Sepax C-Pro and Sefia systems. Flexible options for use with density gradient media or magnetic beads.

Connect Sefia and Sepax C-Pro systems with other Cytiva and third-party equipment using manufacturing automation software.

Cell therapy cell processing workflow with isolation step highlighted. Transparent background.

Consistent cell enrichment with high-quality reagents

For more than 40 years, scientists have enriched cells with reliable results using Ficoll-Paque and Percoll density-gradient media. To enrich mononuclear cells with confidence, we recommend sterile, ready-to-use Ficoll-Paque PREMIUM medium, which is manufactured under a Quality Management System (QMS) certified to ISO 13485:2012. Flexible for use in manual procedures or with Sepax C-Pro and Sefia systems.

Prepare other cell types using low viscosity and low osmolality Percoll PLUS medium. Put our Percoll Calculator to work, so you can prepare the required density with ease.

Flexible cell isolation methods

Choose and refine your approach with Cytiva’s modular systems comprised of instruments, protocol software, and kits. Flexible options allow you to enrich blood components by density-based centrifugation or incubate cells with magnetic beads.

Sefia S-2000 instrument in GMP environment scanning barcode_medium

Streamline cell enrichment

Streamline your cell enrichment from up to 880 mL of apheresis products in a single process with the Sefia Cell Processing Instrument plus appropriate software and kit.

Generic Sefia + software + kit illustration

Reliably separate cells

Reliably separate cells with the preferred method, choosing the flexibility of applications offered by the Sepax C-Pro Instrument plus specific protocol and kit

See Sepax C-Pro system in action for density-based mononuclear cell (MNC) isolation.

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Generic Sepax C-Pro + software + kit illustration

Maximize cell density and maintain quality by combining high-quality media and reagents with automated and functionally closed systems.

Improve process efficiency with an automated, simple, and functionally closed system.

Simplify workflows by automatically sequencing multiple steps. Functionally closed processing helps you manage contamination risk.

Preserve cell viability and function with automated dry freezers and thawers. Connect units across sites and monitor remotely using platform software.