Bioprocess scale-up and technology transfer (DEV4)

About course

Attend this 3-day course to understand advanced late-stage downstream process development, scale-up, and transfer. Learn about process design and optimization for production, and gain an introduction to validation and column packing. The importance of safety and economic issues related to automation will also be discussed. 

 

Students will optimize conditions in a 2-step process and work on maintaining separation performance at increasing scales. Group exercises and discussions will focus on real-life scale-up issues, complementing the hands-on work.

- Focus on smooth scale‑up, well‑prepared technical transfer, and the use of chromatography as a manufacturing tool

-  Process design, optimization, management, and economy

-  Practicals: separation of yeast glucoamylaseisozymes at lab‑, pilot‑, and manufacturing‑scale via desalting and ion exchange chromatography

 

An understanding of chromatography principles and techniques is required for this course. Prior to attending, refresh your knowledge with these courses:

- Regulatory: what is process validation?

- Advanced downstream bioprocess development DEV2

- Introduction to preparative protein chromatography

   

Course dates and locations:

SONGDO, SOUTH KOREA

NOV  17-19, 2026 (KR/EN)

SHANGHAI, CHINA

APR 21-23, 2026 (CN)

AUG 04-06, 2026 (CN)

After the course, you will be able to:

-  Understand the theory and practice of scaling up chromatographic processes

-  Identify critical issues that impact final production performance and economics of bioprocessing

- Suggest improvements for increased productivity, efficiency, effectiveness, and economy

Who should attend?

- R&D scientists or engineers who need to learn more about scale‑up, scale‑down, and operation of chromatographic methods in a production environment

- Scientists at either end of the transfer process, from lab to production and QA/QC, who need to understand the pitfalls and critical issues

 

Review the terms and conditions for Fast Trak™ training courses here.

Review the general course information here.

 

The content below will be accessible after attending the course.