ImageQuant™ TL software is an advanced analysis software for use with Amersham™ ImageQuant™ 800 CCD series imagers and Typhoon™ laser scanners and is specifically designed for images of 1D gels, Western blots, multiwell filter plates, and colony plates. In addition, the analysis toolbox module has several generic tools for quantitative analysis of a wide range of sample types.
Multi-image view facilitates navigation across various analysis windows
Alignment tool enables alignment of images from different acquisition methods, ensuring easy comparison and confidence in results
ÄKTA™ Chromatogram Import function relates each fraction with its corresponding lane on the SDS-PAGE gel
DPI different Image Export options to meet scientific journals image submission requests
Deep Zoom-In tool to evaluate intensity values at pixel level and distinguish among the closest details.
The software includes multiple normalization options to meet your needs for both single and multichannel images.
Single band normalization: Normalizes all bands against a single chosen reference band.
Total protein normalization: Uses the total lane volume of all bands in the lane of a selected reference channel to normalize the bands in the same lane of other channels. For multiplex images.
Housekeeping protein normalization: Identifies the largest band in the reference channel as the housekeeping band, then normalizes each lane against the housekeeping band as reference. For multiplex images.
In-channel normalization: Calculates relative volume of bands to the volume of a reference band or user-selected reference lane.
ÄKTA™ chromatogram import function
Connect chromatograms to SDS-PAGE gel ImageQuant TL software is now available with ÄKTA™ Chromatogram Import function that can relate each fraction with its corresponding lane on the SDS-PAGE gel.
Comparison feature
The Comparison function analyzes and determines lane similarity using mathematical modeling. It can be used to compare purified samples of biopharmaceuticals to reference samples, to determine sample purity of in batch release of drugs, to select a specific fraction from a chromatography run by comparing lanes of different fractions to each other, and more.
ImageQuant™ TL GxP module for regulated environments
A GxP version of the ImageQuant TL software ensures compliance with 21 CFR Part 11, featuring data integrity and traceability, including electronic signatures.