Lentil Lectin Sepharose 4B resin for glycoprotein purification
Lentil Lectin Sepharose 4B resin is used for glycoprotein purification and purification of other carbohydrate-containing molecules.
Lentil Lectin Sepharose™ 4B affinity resin, 25 mL
17044401
Stock on request
Price includes standard shipping and handling
Overview
Lentil Lectin Sepharose 4B resin is used for glycoprotein purification and purification of other carbohydrate-containing molecules.
- Binds molecules that contain α-D-mannose, α-D-glucose, and sterically related sugars.
- Compared to Con A, lentil lectin distinguishes less sharply between glucosyl and mannosyl residues.
- Retains binding in 1% deoxycholate and is valuable for purifying detergent-solubilized membrane proteins.
Capture of proteins with affinity for lentil lectin
Lentil lectin is a metalloprotein that binds reversibly to polysaccharides and glycoconjugates containing glucose or mannose type sugars. Lentil Lectin Sepharose 4B is a group-specific adsorbent that is well-suited to purifying membrane proteins and viral glycoproteins.
Successful use in published research
This affinity resin is used in a variety of applications, including:
- Isolation of modified HIV-1 envelope glycoproteins to study effects on the CD4 binding site
- Purification of native and recombinant human dopamine beta-hydroxylase expressed in Drosophila Schneider 2 cells for comparison studies.
Product specifications
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Lentil Lectin Sepharose™ 4B affinity resin, 25 mL
17044401
Stock on request
Product availability is not guaranteed and subject to change.
