MacroCap™ SP
MacroCap SP is a cation exchanger designed for the purification of large biomolecules such as polyethylene glycol (PEG)-modified proteins (i.e., PEGylated proteins) that are intended for use as biopharmaceuticals.
MacroCap™ SP
MacroCap SP is a cation exchanger designed for the purification of large biomolecules such as polyethylene glycol (PEG)-modified proteins (i.e., PEGylated proteins) that are intended for use as biopharmaceuticals.
Pack size
Overview
- Strong cation exchanger for PEGylated proteins and other large biomolecules.
- High purity and yield of PEGylated proteins at high sample loads.
- Highly porous base matrix makes extensive surface area available for adsorption of large molecules.
MacroCap SP is a cation exchanger designed to separate PEGylated proteins and other large biomolecules. It allows separation of mono- from oligo- and non-PEGylated proteins with high selectivity under high load conditions. MacroCap SP is based on acrylamide-dextran copolymer resins with mass transfer properties suitable for large biomolecules. The base matrix is highly porous, which gives high available surface area for adsorption of PEGylated proteins. The large pore size also makes MacroCap SP suitable for binding other large proteins, e.g. IgM.
MacroCap SP is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess resins range, MacroCap SP meets industrial demands with security of supply and comprehensive technical and regulatory support.
