MidGee™ Hoop microfiltration hollow fiber tangential flow cartridges
Tangential flow microfiltration hoop cartridges with polysulfone membrane that allow easy scaling even with small product volumes.
MidGee™ Hoop microfiltration hollow fiber tangential flow cartridges
Tangential flow microfiltration hoop cartridges with polysulfone membrane that allow easy scaling even with small product volumes.
Variant
Overview
- Rapid concentration and/or diafiltration of critical biological solutions.
- Full range of MF pore sizes and lumen diameters.
- 60 cm and 110 cm path lengths match pilot- and production-scale designs.
- Autoclavable and compatible with aqueous solutions and most alcohols.
- High product recoveries with minimal shear denaturation.
- No wall effects to distort scale-up projections as with plate and frame devices.
Scale up or down easily
Throughout the R&D process, access to product is often limited. As a result, investigations into optimization of operating conditions are sometimes postponed or avoided entirely. Now scale-up and scale-down using minimum product volumes is easy with MidGee Hoop hollow fiber cartridges.
Hoop cartridges provide all the critical features of full production scale in a miniature tangential flow device, allowing simulation of process parameters, including path length, with minimal solution volume and pump capacity.
The uniform flow path design from laboratory- to production-scale makes hollow fibers the most attractive of the various tangential flow configurations for linear scale-up.
Small is beautiful
MidGee Hoop cartridges are optimized for use in the compact MidJet Cross Flow Filtration System, which includes
- A miniature peristaltic pump with exchangeable saddles to accommodate size 14 and 16 tubing
- Reservoirs for retentate, diafiltrate and permeate
- Precision backpressure control valve
- A convenient platform for mounting the cartridge and pump with recesses to accommodate three reservoirs
