10 membrane volumes/min (MV/min) is typical (higher flow rates can be achieved specific to your process).
For large molecules such as viral vectors, 5 MV/min or less is typical to faciltate favourable process outcomes.
Mustang™ Q and S chromatography membranes in XT Acrodisc™ capsule
Disposable membrane ion-exchange chromatography units for scale-down process development
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1. Chromatography Adsorber
2. Pore size
Mustang Q and S chromatography membranes in XT Acrodisc capsule
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Overview
Mustang™ XT Acrodisc™ units, available in Q and S chemistries, are suitable for scale-down process development work in a variety of downstream process applications.
- Fast, easy-to-use, scale-down Mustang membrane unit facilitates process development work
- Device volume of < 1 mL minimizes sample volume requirements
- 16 layers of Mustang membrane allow easy scale-up to Mustang membrane pilot- and process-scale capsules
- Units achieve flow rates of up to 10 membrane volumes per minute (MV) without affecting performance
- Female Luer lock inlet and outlet simplifies use with typical low-pressure chromatography systems
- Disposable 25 mm units.
Mustang Q Membrane
Mustang Q membrane is anion-exchange support with pendant quaternary amine functional groups in a cross-linked polymeric coating on a 0.8-micron pore-size membrane. This gives high dynamic capacities for high molecular weight products such as DNA, plasmids, or even particles as large as viruses.
Mustang S Membrane
Mustang S membrane is cation-exchange support with pendant sulfonic functional groups in a cross-linked polymeric coating on a 0.65 µm pore-size membrane. This gives high dynamic capacities for high molecular weight products such as IgG, Factor VIII, and some viruses.
Mustang XT Acrodisc units, available in Q and S chemistries, are ideal for scale-down process development work in a variety of downstream process applications. A membrane volume of < 1 mL reduces the amount of sample required for evaluation, and the female Luer lock inlet and outlet simplifies connection to typical low-pressure chromatography systems. The open-pore structure eliminates diffusion limitations of conventional macroporous sorbents, allowing biomolecules to access all binding sites by the convective flow. In addition, the large pores eliminate the size exclusion effect allowing full access to the binding chemistry for very large proteins, plasmids, and viruses.
Product specifications
Showing 2 products
Mustang™ Q AIEX membrane in XT Acrodisc™ capsule, 0.86 mL (4/Pk)
MSTGXT25Q16
In stock99 available
Mustang™ S CIEX membrane in XT Acrodisc™ capsule, 0.86 mL (4/Pk)
MSTGXT25S16
In stock6 available
Product availability is not guaranteed and subject to change.
