OligoPilot™ oligonucleotide synthesizer
The OligoPilot™ oligonucleotide synthesizer can produce more than 100 kg/yr for clinical trials, covering a range of 10 to 150 mmol
OligoPilot™ oligonucleotide synthesizer
The OligoPilot™ oligonucleotide synthesizer can produce more than 100 kg/yr for clinical trials, covering a range of 10 to 150 mmol
Overview
Synthesize oligonucleotides at scales of 10–150 mmol for early to mid-phase clinical trials or for diagnostic kits. This robust system has a footprint small enough to fit in a walk-in fume hood. Scale up easily with common UNICORN™ control software.
- Based on more than 30 years of collaboration with leading oligonucleotide pharma.
- Uses UNICORN™ control software for seamless scale-up from ÄKTA™ oligopilot™ plus oligo synthesizer to full-scale manufacturing with the OligoProcess™ system.
- Inline monitoring enables high degree of process control.
- Based on the same robust components as the OligoProcess™ synthesizer.
- Installation and Operation Qualification (IQ/OQ) documentation and performance support are available.
- Change control notification support available.
Fast coupling
Produce one batch per day with fast-coupling capability. With well-trained staff, efficient standard operating procedures (SOPs), and secure supply, the OligoPilot™ oligonucleotide synthesizer can be part of a manufacturing train producing > 100 kg of oligonucleotides in a year.
Small footprint
The instrument fits easily into a walk-in fume hood. It is designed to be explosion proof according to ATEX Zone 2. Please refer to local legislation for guidance of local requirements.
Seamless workflow
UNICORN™ control software offered with this and other Cytiva products makes it easy to align your oligonucleotide synthesis with downstream processing, chromatography, and filtration, supporting an oligonucleotide development and manufacturing workflow.
