PreDictor™ MabSelect SuRe prepacked 96-well plates
MabSelectSure alkali-resistant protein A resin, prepacked in 96-well plates for high throughput process development.
Chromatography resin volume/well
Overview
- Supports high-throughput process development (HTPD) by allowing parallel screening of chromatographic conditions using a 96-well plate format.
- Allows fast and efficient evaluation of parameters for binding/wash/elution conditions, and resins benchmarking.
- Results show good correlation with data obtained by column chromatography.
- Each well is prefilled with defined amounts of Cytiva BioProcess chromatography resins.
- Can be used with centrifugation or vacuum, manually or in automated robotic systems.
- Assist software supports the PreDictor workflow from set-up of experimental design to data evaluation.
About MabSelect SuRe resin
MabSelect SuRe has an alkali-tolerant rProtein A ligand that allows the use of rigorous and cost-effective CIP and sanitization protocols based on 0.1 to 0.5 M NaOH. Further, the ligand is protease stable leading to lower ligand leakage.
The novel ligand construct of MabSelect SuRe has been proven to have an increased stability towards proteases. Therefore, the level of leakage of the MabSelect SuRe ligand during elution is low.
MabSelect SuRe has been demonstrated to give generic elution conditions for different monoclonal antibodies, which is an advantage when designing generic purification platform processes. This feature is also correlated to the construction of the MabSelect SuRe ligand
About PreDictor MabSelect SuRe plates
PreDictor plates are disposable, 96-well filter plates for parallel screening of resins and chromatographic conditions such as binding, wash, and elution conditions.
- Screen different chromatography resins simultaneously using dedicated screening plates, or more thoroughly using plates containing a single resin.
- Different applications require different amounts of resins in the wells, and we offer a wide range of PreDictor plates containing different chromatography resins at different volumes.
- Data generated using PreDictor plates show good correlation with data from chromatography columns, making the plates an excellent tool for initial screening of process conditions.
Assist software supports the PreDictor workflow from set-up of experimental design to data evaluation.
Prepacked columns and other formats
Bulk resin
MabSelect SuRe in bottles for batch purification or packing your own columns.
Process development scale – prepacked
HiScreen MabSelect SuRe columns – optimized for method and process development .
Lab/research scale – prepacked for manual purification
HiTrap MabSelect SuRe columns – for easy use with a syringe, peristaltic pump, or chromatography system.
Lab/research scale – prepacked for automated purification and analysis
HiTrap MabSelect SuRe columns – for easy use with a syringe, peristaltic pump, or chromatography system.
Process scale purification – prepacked
ReadyToProcess MabSelect SuRe columns – 1 L and larger columns for clinical manufacturing that avoid the need for cleaning and cleaning validation.
Learn about MabSelect SuRe, prepacked HiScreen MabSelect SuRe, HiTrap MabSelect SuRe, ReadyToProcess MabSelect SuRe columns or PreDictor Robocolumns MabSelect SuRe
