Drug product filtration systems

The Cytiva™ drug product filtration system operates using configurable recipe-controlled phases to automatically perform terminal sterilization prior to filling with maximum product recovery using standard flow kits. It has been designed to support EU GMP Annex 1: Manufacture of sterile medicinal products requirements for contamination control strategies with automated in situ pre-use post-sterilisation integrity testing (PUPSIT) and post-use integrity testing of sterile filters.

The Cytiva™ manual drug product filtration system performs the sterile filtration of drug product. The system is designed to support the EU GMP Annex 1: Manufacture of sterile medicinal products by manually performing pre-use post sterilization integrity testing (PUPSIT) of the sterilizing-grade filters.