Lentiviral vector production using single-use bioreactors
A robust and scalable process in HEK293T cells with HyClone™ peak expression medium for growth and transfection.
For cell and gene therapy workflows
Lentiviral vectors are common viral vectors for therapeutic purposes. Several approved CAR T cell therapies and gene therapies use lentiviral vectors, with more in the pipeline. Developing an efficient process for producing a lentiviral vector-based therapy is challenging due to low stability of these enveloped viruses.
Primary clarification of lentiviral vectors
In this study, we discuss development of a primary clarification protocol to separate LV from bioreactor-derived suspension cells and debris using a scalable filter train.
Improving lentiviral vector downstream processing workflows
In this article we discuss process development pain points of a modern downstream workflow and ways to address them.
Development and manufacturing solutions
Simplify and streamline your manufacturing process with integrated solutions, speeding time to market and reducing overall cost of goods. A simplified process, using standard, equipment, qualified single-use system designs and components, lowers the risk for operator error.
Process development services
Process development services Use our know-how to simplify and accelerate your development and meet your process milestones.
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Additional resources
- Viral vector tips
- Regulatory insights
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Related applications
- Cell therapy
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Other gene delivery
- AAV vector
- Adenovirus