Chromaflow™ chromatography columns
A family of convenient process-scale columns with a patented nozzle in the top and bottom of the column that allows packing, unpacking, and cleaning in place. Chromaflow columns are a natural choice when scaling up from BPG columns.
Chromaflow™ chromatography columns
A family of convenient process-scale columns with a patented nozzle in the top and bottom of the column that allows packing, unpacking, and cleaning in place. Chromaflow columns are a natural choice when scaling up from BPG columns.
Choose your product
1. Column i.d.
2. Material [Bed Support]
3. Nozzle Type
4. Porosity
5. Bed height
Overview
A family of convenient process-scale columns with a patented nozzle in the top and bottom of the column that allows packing, unpacking, and cleaning in place. Chromaflow columns are a natural choice when scaling up from BPG columns.
- For capture or intermediate purification.
- Scalable up to 2 m in diameter.
- Easy to operate and maintain. Packing knowledge and application support available.
- Convenient, pack-in-place nozzle.
- Closed system improves safety.
- Easy-to-use Chromaflow packing station facilitates packing procedure.
- All plastomers in contact with process flow are tested and approved to USP Class VI.
- All metallic materials in construction are fully traceable.
- Installation and Operational Qualification Documentation Packages and service and maintenance contacts available.
Do it all without even lifting the lid
With Chromaflow columns, packing, operation, unpacking, and cleaning can be performed without removing the lid or adapter – all due to the design of the nozzle in both the top and bottom end-pieces. With the establishment of packing protocols for individual resins, large-scale chromatography is more convenient, scalable and safer for both the operators and the product. Chromaflow columns are intended for GMP production.
How it works
Nozzles sit in both the top and bottom of the column allowing packing in either an upward or downward direction. There are three nozzle positions:
- Mid-position, for priming and packing. The bottom nozzle extends part of the way (mid-position) into the column. The top nozzle is fully retracted. Slurry enters the column via the bottom nozzle and excess liquid exits via the top mobile phase outlet. After packing, the slurry lines are isolated from the mobile phase and can be cleaned independently from the rest of the column.
- Retracted, for running. The top and bottom nozzles are retracted. Mobile phase enters the column directly into an annulus immediately behind the bed support. The annulus is cut through at an angle to ensure that the linear flow rate is kept constant during distribution of the mobile phase across the bed.
- Fully extended into the column for unpacking and cleaning. In this position, both bottom and top nozzles are fully extended into the column, thereby exposing a third passage through which resin leaves the column. Cleaning solution can be pumped through the nozzles and sprayed into the column. In this way, the column is easily and effectively cleaned without exposing the interior or the resin to the outside, or without dismantling the column.
The nozzle also enables isolation of slurry lines from the mobile phase during operation, allowing removal of residual resin and cleaning of the slurry lines independently of the rest of the column.
Product specifications
Showing 90 products
Chromaflow 400 mm, SFP manual nozzle, 200-400 mm, 10 SS
11001180
Chromaflow 400 mm, SFP manual nozzle, 300-500 mm, 10 SS
11001182
Chromaflow 400 mm, SFP manual nozzle, 200-400 mm, 20 SS
11001183
Chromaflow 400 mm, SFP manual nozzle, 300-500 mm, 20 SS
11001184
Chromaflow 400 mm, SFP manual nozzle, 100-300 mm, 20 PE
11001185
Chromaflow 400 mm, SFP manual nozzle, 200-400 mm, 20 PE
11001186
Chromaflow 400 mm, SFP manual nozzle, 300-500 mm, 20 PE
11001187
Chromaflow 400 mm, SFP automatic nozzle, 200-400 mm, 10 SS
11001188
Chromaflow 400 mm, SFP automatic nozzle, 100-300 mm, 10 SS
11001189
Chromaflow 400 mm, SFP automatic nozzle, 300-500 mm, 10 SS
11001190
Chromaflow 400 mm, SFP automatic nozzle, 100-300 mm, 20 SS
11001191
Chromaflow 400 mm, SFP automatic nozzle, 200-400 mm, 20 SS
11001192
Chromaflow 400 mm, SFP automatic nozzle, 300-500 mm, 20 SS
11001193
Chromaflow 400 mm, SFP automatic nozzle, 100-300 mm, 20 PE
11001194
Chromaflow 400 mm, SFP automatic nozzle, 200-400 mm, 20 PE
11001195
Chromaflow 400 mm, SFP automatic nozzle, 300-500 mm, 20 PE
11001196
Chromaflow 1000 mm, manual nozzle, 100-300 mm, 10 SS
18115010
Chromaflow 400 mm, manual nozzle, 100-300 mm, 10 SS
18115040
Chromaflow 600 mm, manual nozzle, 100-300 mm, 10 SS
18115060
Chromaflow 800 mm, manual nozzle, 100-300 mm, 10 SS
18115080
Chromaflow 400 mm, automatic nozzle, 100-300 mm, 10 SS
18115741
Chromaflow 400 mm, manual nozzle, 200-400 mm, 10 SS
18115742
Chromaflow 400 mm, automatic nozzle, 200-400 mm, 10 SS
18115743
Chromaflow 400 mm, manual nozzle, 300-500 mm, 10 SS
18115744
Chromaflow 400 mm, automatic nozzle, 300-500 mm, 10 SS
18115745
Chromaflow 600 mm, automatic nozzle, 100-300 mm, 10 SS
18115761
Chromaflow 600 mm, manual nozzle, 200-400 mm, 10 SS
18115762
Chromaflow 600 mm, automatic nozzle, 200-400 mm, 10 SS
18115763
Chromaflow 600 mm, manual nozzle, 300-500 mm, 10 SS
18115764
Chromaflow 600 mm, automatic nozzle, 300-500 mm, 10 SS
18115765
Chromaflow 800 mm, automatic nozzle, 100-300 mm, 10 SS
18115781
Chromaflow 800 mm, manual nozzle, 200-400 mm, 10 SS
18115782
Chromaflow 800 mm, automatic nozzle, 200-400 mm, 10 SS
18115783
Chromaflow 800 mm, manual nozzle, 300-500 mm, 10 SS
18115784
Chromaflow 800 mm, automatic nozzle, 300-500 mm, 10 SS
18115785
Chromaflow 1000 mm, automatic nozzle, 100-300 mm, 10 SS
18115811
Chromaflow 1000 mm, manual nozzle, 200-400 mm, 10 SS
18115812
Chromaflow 1000 mm, automatic nozzle, 200-400 mm, 10 SS
18115813
Chromaflow 1000 mm, manual nozzle, 300-500 mm, 10 SS
18115814
Chromaflow 1000 mm, automatic nozzle, 300-500 mm, 10 SS
18115815
Chromaflow 400 mm, manual nozzle, 100-300 mm, 20 SS
18115940
Chromaflow 400 mm, automatic nozzle, 100-300 mm, 20 SS
18115941
Chromaflow 400 mm, manual nozzle, 200-400 mm, 20 SS
18115942
Chromaflow 400 mm, automatic nozzle, 200-400 mm, 20 SS
18115943
Chromaflow 400 mm, manual nozzle, 300-500 mm, 20 SS
18115944
Chromaflow 400 mm, automatic nozzle, 300-500 mm, 20 SS
18115945
Chromaflow 600 mm, manual nozzle, 100-300 mm, 20 SS
18115960
Chromaflow 600 mm, automatic nozzle, 100-300 mm, 20 SS
18115961
Chromaflow 600 mm, manual nozzle, 200-400 mm, 20 SS
18115962
Chromaflow 600 mm, automatic nozzle, 200-400 mm, 20 SS
18115963
Chromaflow 600 mm, manual nozzle, 300-500 mm, 20 SS
18115964
Chromaflow 600 mm, automatic nozzle, 300-500 mm, 20 SS
18115965
Chromaflow 800 mm, manual nozzle, 100-300 mm, 20 SS
18115980
Chromaflow 800 mm, automatic nozzle, 100-300 mm, 20 SS
18115981
Chromaflow 800 mm, manual nozzle, 200-400 mm, 20 SS
18115982
Chromaflow 800 mm, automatic nozzle, 200-400 mm, 20 SS
18115983
Chromaflow 800 mm, manual nozzle, 300-500 mm, 20 SS
18115984
Chromaflow 800 mm, automatic nozzle, 300-500 mm, 20 SS
18115985
Chromaflow 1000 mm, manual nozzle, 100-300 mm, 20 SS
18116010
Chromaflow 1000 mm, automatic nozzle, 100-300 mm, 20 SS
18116011
Chromaflow 1000 mm, manual nozzle, 200-400 mm, 20 SS
18116012
Chromaflow 1000 mm, automatic nozzle, 200-400 mm, 20 SS
18116013
Chromaflow 1000 mm, manual nozzle, 300-500 mm, 20 SS
18116014
Chromaflow 1000 mm, automatic nozzle, 300-500 mm, 20 SS
18116015
Chromaflow 400 mm, manual nozzle, 100-300 mm, 20 PE
18116140
Chromaflow 400 mm, automatic nozzle, 100-300 mm, 20 PE
18116141
Chromaflow 400 mm, manual nozzle, 200-400 mm, 20 PE
18116142
Chromaflow 400 mm, automatic nozzle, 200-400 mm, 20 PE
18116143
Chromaflow 400 mm, manual nozzle, 300-500 mm, 20 PE
18116144
Chromaflow 400 mm, automatic nozzle, 300-500 mm, 20 PE
18116145
Chromaflow 600 mm, manual nozzle, 100-300 mm, 20 PE
18116160
Chromaflow 600 mm, automatic nozzle, 100-300 mm, 20 PE
18116161
Chromaflow 600 mm, manual nozzle, 200-400 mm, 20 PE
18116162
Chromaflow 600 mm, automatic nozzle, 200-400 mm, 20 PE
18116163
Chromaflow 600 mm, manual nozzle, 300-500 mm, 20 PE
18116164
Chromaflow 600 mm, automatic nozzle, 300-500 mm, 20 PE
18116165
Chromaflow 800 mm, manual nozzle, 100-300 mm, 20 PE
18116180
Chromaflow 800 mm, automatic nozzle, 100-300 mm, 20 PE
18116181
Chromaflow 800 mm, manual nozzle, 200-400 mm, 20 PE
18116182
Chromaflow 800 mm, automatic nozzle, 200-400 mm, 20 PE
18116183
Chromaflow 800 mm, manual nozzle, 300-500 mm, 20 PE
18116184
Chromaflow 800 mm, automatic nozzle, 300-500 mm, 20 PE
18116185
Chromaflow 1000 mm, manual nozzle, 100-300 mm, 20 PE
18116210
Chromaflow 1000 mm, automatic nozzle, 100-300 mm, 20 PE
18116211
Chromaflow 1000 mm, manual nozzle, 200-400 mm, 20 PE
18116212
Chromaflow 1000 mm, automatic nozzle, 200-400 mm, 20 PE
18116213
Chromaflow 1000 mm, manual nozzle, 300-500 mm, 20 PE
18116214
Chromaflow 1000 mm, automatic nozzle, 300-500 mm, 20 PE
18116215
Chromaflow 400 mm, small flow path manual nozzle, 100-300 mm, 10 SS
18117053
Chromaflow 400 mm, small flow path manual nozzle, 100-300 mm, 20 SS
18117612
Product availability is not guaranteed and subject to change.
