Human Fab Capture Kit, type 2
Reagents for capture of human Fab fragments as ligands in biomolecular interaction analysis.
Designed for use with Biacore 8K+, and Biacore 8K (larger kit component volumes than in Human Fab Capture Kit) but can be used with all other Biacore systems.
Overview
Reagents for capture of human Fab fragments as ligands in biomolecular interaction analysis.
Designed for use with Biacore 8K+, and Biacore 8K (larger kit component volumes than in Human Fab Capture Kit) but can be used with all other Biacore systems.
- Early selection of binders enabled through kinetics screening by high resolution off-rate ranking.
- Broad framework specificity. Kappa and lambda types of human Fab fragments captured.
- Excellent assay performance. Fab binder with high capture efficiency and stability.
Intended Use
The main applications of Human Fab Capture Kit, type 2 are screening and characterization of human Fab fragments generated from phage display (purified or directly from crude cell lysates or periplasmic extract).
Human Fab Binder Description
Human Fab Binder is a mixture of two monoclonal antibodies recognizing, respectively, kappa and lambda subtypes of Human Fab fragment light chains. It binds specifically to the Fab region of human antibodies and no binding to the Fc region has been observed. It recognizes most subtypes of both kappa and lambda light chains and does not cross-react with Fab from other species. In addition, no non-specific binding from cell lysate or cell culture medium has been observed.
