ÄKTA ready is a single-use liquid chromatography system built for process scale-up and manufacturing. The systems uses disposable flow paths and prepacked columns that enable flexibility and speed in bioprocessing.
- Simple exchange of the complete flow path eliminates the need for system cleaning, including validation.
- Reduced downtime between products/batches due to simpler procedures, improving economy and productivity.
- Risk for cross-contamination between products/batches is minimized.
- Supports two disposable flow paths with different diameters to allow a wide range of flow rates, increasing scalability.
- Accompanied by extensive product documentation.
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The ÄKTA ready system comprises an ÄKTA ready chromatography unit, UNICORN control software, and disposable ÄKTA ready flow kits including detection flow cells. Two standard versions of ÄKTA ready are available: one version is for isocratic use and the one with gradient capability. Modified versions of the system are available upon request.
The system can be Installation and Operation Qualification (IQ/OQ) certified by the customer or by a certified specialist. A UNICORN wizard guides the operator on how to install the flow kit and performs an installation test prior to running the system.
Part of ReadyToProcess single-use platform
The ReadyToProcess platform consists of ready-to-use solutions for entire manufacturing processes. After a purification step has been completed using ÄKTA ready, the single-use flow paths (i.e., ÄKTA ready flow kits and gradient flow sections) are disposed. The flow paths can be changed quickly, with a downtime of less than 1 h. This saves time, capital investment, start-up costs, labor costs, and costs for consumables.
ReadyToProcess columns can be reused for several batches within the same purification campaign.
Robust and hygienic design
The ÄKTA ready system is resistant to chemical agents used in protein recovery, including buffer solutions for adsorption, elution and washing, and regeneration and cleaning solutions.
All material is of proven quality, and the flow paths are disposable. All wetted materials are fully biocompatible (USP class VI), and of animal-free origin or compliant with EMA/410/01.
The materials used are traceable back to their production batches. The flow paths are produced under controlled conditions and packed in a clean room environment (class ISO 7) using validated protocols.
The disposable flow paths are delivered gamma-irradiated or autoclaved.
Regulatory Product documentation and services
Process safety is an integral part of the ÄKTA ready system and this includes the exchangeable flow paths. ÄKTA ready flow paths are supported with an extensive documentation package and support.
OptiRun service solutions offer a comprehensive range of options that can be customized to your asset-management needs and desired outcomes. Learn more about service agreements and lifecycle support for your equipment.
Change Control Notifications
Our web-based Change Control Notification (CCN) service ensures that you are notified about changes that could potentially impact your product or process.
The CCN service is available for free by subscription at the Regulatory Support website.Read less
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