Minimizing cell lysis during clarification
Selection and design of depth filtration process to minimize cell lysis and particle counts.
Direct clarification using depth filtration
Scalable and compact single-use solutions are the go-to choice for the economic clarification of a broad range of cell cultures and turbid intermediates. Cellulose-based construction provides high capacity for biomass without the need for centrifugation or process additives.
Direct clarification using body-feed
The clarification of extremely high turbidity and high biomass cell cultures may not be economic with depth filtration alone. The addition of diatomaceous earth and other process additives can help and requires removal before further processing is possible.
Process control and automation
Control is an essential contributor to assuring repeatable filter performance and achieving the harvest quality attributes. Full automation simplifies the operation, reduces process risk, and frees operator time while enabling full data capture, trending and integration with electronic batch records.
Stax™ mAx platform
Robust single-use depth filtration for the economic clarification of harvested cell culture fluids.
Allegro™ Connect depth filtration system
Fully automated, configurable control platform for clarification. A Pall™ Life Sciences product.
Stax™ single-use depth filtration
A range of media grades to meet your lab, clinical, and commercial production clarification needs.
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Related applications
- Monoclonal antibodies
- Viral vectors
- Vaccines
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Other filtration solutions
- Bioburden filtration
- Sterile filtration
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Fluid handling solutions
- Liquid handling bags and assemblies
- Storage bins and assemblies
- Single-use connectors