Biopharma’s scale-up challenge
As manufacturing bottlenecks persist, how will the industry keep up with demand?
Scaling up your bioprocess from pilot through to the target production volume can be complex. Good choices help establish a scalable process that allows you to increase throughput and reduce the need for additional process optimization. These choices need to maintain critical control points to safeguard product quality and also maximize efficiency as you scale up.
The resources below can help get you started. If you're looking for a trusted partner in your scale-up journey, a helping hand is just a call away.
Scale-up and tech transfer
Downstream bioprocess scale-up and technology transfer from laboratory to GMP-compliant commercial production
Scaling bioprocesses while minimizing CMC risk
Successful chemistry, manufacturing, and control activities streamline drug development without compromising quality or efficacy
Bioburden control
How to mitigate risk associated with bioburden.
Explore our biotherapeutic solutions with our app
Discover our suite of end-to-end solutions for mAb production and see how they fit in a facility
X-Platform bioreactors
Single-use, scalable bioreactors
Xcellerex™ magnetic mixer
2000 and 3000 L single-use mixing systems for your large-scale applications.
ÄKTA ready™ XL
Adapting single-use chromatography to manufacturing scale
ÄKTA readyflux™ XL
Automated single-use filtration at large scale
ÄKTA process™
A highly flexible chromatography system for process scale-up and large-scale manufacturing
Allegro™ Connect bulk fill
An automated filtration and filling system
-
Helpful tools
- Chromatography Tools