Biotherapeutic drug discovery

White paper
  • White paper
  • Application Notes
  • Articles
Key SPR applications
  • Key SPR applications
  • Bioanalytics in drug development and QC
  • Biotherapeutic drug discovery
  • Protein interaction analysis
  • Small molecule drug discovery
  • Get started with SPR interaction analysis
  • Biacore SPR products
  • Biacore software downloads
  • Interaction analysis with Biacore SPR systems
  • Training courses

White Paper

  • Biacore systems in discovery and early-stage development of biotherapeutic antibodies

Application Notes

  • Assessing long-term glucose regulation by measurement of glycated hemoglobin using Biacore 8K

  • Biacore comparability tool for quantitating binding similarities in IgG Fcγ receptor analysis

  • Binding-mode sensitive reagents. A new method for monitoring the integrity of humanized monoclonal antibodies using surface plasmon resonance.

  • Lead selection of biologics with low clearance due to receptor-mediated endocytosis

  • Binding affinities of recombinant Protein L, Protein A, and Protein G

Articles

  • Epitope binning: a critical step in antibody selection

    Avoid false negatives due to unstable binding of antigen to primary antibody

  • Surface plasmon resonance (SPR): Three decades of SPR supporting target-based drug discovery