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Small molecule drug discovery

White paper
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Key SPR applications
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  • Bioanalytics in drug development and QC
  • Biotherapeutic drug discovery
  • Protein interaction analysis
  • Small molecule drug discovery
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White Paper

  • Outstanding sensitivity for confident label-free interaction analysis

  • Biacore systems in small molecule discovery

Application Notes

  • Fragment library screening against the Hepatitis C drug target, NS5B 1b, in the search for novel allosteric drug leads

  • Characterizing lead compounds using label-free interaction analysis: Blocking T-cell activation in rheumatoid arthritis therapy

  • Profiling inhibitor selectivity for PARP protein family members

Articles

  • Reducing attrition early in discovery

  • Surface plasmon resonance (SPR): Three decades of SPR supporting target-based drug discovery

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