Change control notifications

Purchased a Cytiva product? Stay informed about product updates and ensure ongoing compliance.

Stay ahead of product changes

Working in a regulated environment? Even small changes to materials or components can impact your process. Cytiva’s change control notification (CCN) service helps you stay informed and compliant. Learn how to activate notifications for your products and receive updates directly to your inbox.

Cytiva releases CCNs in accordance with the standard for Cytiva change control and notification process, available below.

How to get started with CCNs

Register or log in with company email address (use a generic company email to maintain change continuity).
Find your products in the regulatory documentation section.
Subscribe and stay updated — receive email notifications when changes are published.

Subscribe to CCNs

What you get with CCN

With change control notification (CCN), you can:

Get notified

Receive email alerts when a new change is published.

Track history

Access previously published change notifications for each product.

Download documents

Save change notifications in PDF format for your records.

Stay informed as a team

Use a generic company email for sustainable change management.

Products covered by the CCN service

Cytiva’s change control notification (CCN) service helps you stay compliant by notifying you about changes that may impact your products or processes.

The service covers:

Bioprocess hardware, software,
Single-use disposables,
Chromatography resins,
Cell culture products,
Cell & gene therapy products,
Biacore™ systems,
Bioprocess filtration products,
Medical products.

How we manage product changes

We document and track all products and product related changes handled through our change control process. Every change is assessed for risk and impact, and validation is considered where needed. Based on the outcome, a change control notification may be published. Some types of changes are always communicated via a CCN.

Examples of changes that may trigger a customer notification:

Change of manufacturing site,
Change of raw material,
Change of specification limits,
Change of label or packaging material,
Change of critical subcontractor.

Standards and supporting materials

Explore key materials that support your understanding of Cytiva’s change control notification service.

Standard for Cytiva change control process for designated products

View documentation

Standards for Cytiva change control and notification process for Pall Medical products

View documentation

Flyer about change control notification service

Download documentation

Related regulatory resources

Regulatory support documentation

Quality management

Regulatory statements

Extractables information

Frequently asked questions

What is a change control notification (CCN)?

CCN is a web-based notification system concerning designated Cytiva products, where you subscribe to CCN for products of interest. When a notification is published for one of your subscribed products you will receive an email. CCN contains information regarding changes associated with the manufacture of products, in accordance with our standards.

Read more about the products concerned and our standards on this page.

Why aren't CCN subscriptions automatically included with my RSF/VSF/VG subscription?

To avoid email notifications being classified as spam (unsolicited email), the system is designed so that the recipient must actively select to receive email notifications.

Who should I contact if I have questions about a change control notification or a regulatory support document?

For ACMS/Accelerator™ documentation center support, contact ACMS-doccontrol@cytiva.com

For all other requests, find your local contact at www.cytiva.com/contact

I have questions about my subscriptions. Who do I contact?

For ACMS/Accelerator™ documentation center account subscriptions, contact ACMS-doccontrol@cytiva.com. For all other subscriptions, contact RegulatorySupport@cytiva.com

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