Buffer management

The ÄKTA process™ automated chromatography system is designed for process scale-up and large-scale biomanufacturing. As your process evolves, choose from over a million possible configurations and add pumps, sensors or inline dilution functionality as needed.

The Allegro™ Connect buffer management system provides buffer on demand. It is a flexible system designed for pilot scale, clinical batches and commercial production to ensure that the right buffer is delivered at the right time, providing an efficient, streamlined workflow. The modular system design enables up to six high volume process buffers to be supplied as required, one at a time, directly to the batch unit operation such as chromatography or tangential flow filtration (TFF) based on buffer inline-dilution (ILD) and utilizing a single-use flow path. Multi-column chromatography (MCC) application buffer requirements can also be met by the Allegro Connect buffer management system, delivering a maximum of four process buffers at the same time to the MCC chromatography system.

BioProcess™ IC System is a buffer management system that allows on demand production of buffers from single-component, highly concentrated stock solutions of salt, acid, and base, diluted with water using inline conditioning technology. Accuracy is ensured through dynamic control using different modes of feedback control.  See overview video on  inline conditioning (IC) technology  (YouTube).