The Xcellerex™ Automated Perfusion System (APS) is designed to streamline upstream perfusion applications by integrating multiple functions into a single-use system. Here are some key benefits of the system:
Simplify operations: Integrate all perfusion operations into a single platform, including bioreactor, cell retention, fluid management, and automation. Access everything via one user interface that generates a single batch report.
Minimize capital expenditure: Use a single system that supports your volume needs from less than 50 L to 500 L.
Achieve high-density cell cultures: The low-shear recirculation pump minimizes impact on cell viability, ensuring high-density cultures.
Maintain optimal filter performance: Intelligent filter switching minimizes user intervention and eliminates the need for a backup system.
Reduce manual interactions: Automated liquid management controls media and permeate bin switching, reducing the need for manual intervention.
Maximize flexibility: Utilize standard ReadyToProcess™ hollow fiber cartridges in a wide range of sizes for both microfiltration and ultrafiltration applications.
Function: Transfers cell culture supernatant from bioreactor to filter.
Cell Harvest: Allows bioreactor to be emptied post-run without external pump.
Filter Management: Supports up to two filters with intelligent switch feature based on performance.
Permeate flow path
Function: Directs product or spent media to collection vessel.
Automated Switch: Automatically switches to new collection vessel when full.
Components: Supports up to two single-use permeate collection bags, pressure sensor, flow meter, sampling line.
Perfusion media flow path
Function: Delivers perfusion feed media to bioreactor.
Components: Supports up to two single-use media storage bags on weigh scales for continuous weight monitoring.
Cell bleed flow path
Function: Achieves desired cell density through automated cell bleed.
Components: Bin on weigh scale for feedback, supports continuous or bolus bleed mode.
Perfusion bag
Design: Seamless connectivity to Xcellerex™ bioreactor and flow kits, designed for perfusion applications.
Alternating permeate flow (APF)
Function: Defines high and low setpoints for permeate flow to encourage filter longevity by preventing lodging of cell debris.
Integrated control with AVEVA™ software
Software: AVEVA™ (formerly Wonderware™) running on Microsoft® Windows® server.
User Interface: X-Station with touchscreen, keyboard, and mouse.
Features: Perfusion overview screen, status of instrument modules, alarm and event notifications, graphical user interface (GUI) for monitoring and control.
Product specifications
Showing 1 products
Xcellerex APS main instrument
29297750
Stock on request
On request
Product availability is not guaranteed and subject to change.
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