NanoAssemblr™ Ignite and Ignite+ cartridges
NanoAssemblr™ Ignite system cartridges feature NxGen™ mixing technology that allows scale-up through a single mixer from mL/min to L/h.
NanoAssemblr™ Ignite and Ignite+ cartridges
NanoAssemblr™ Ignite system cartridges feature NxGen™ mixing technology that allows scale-up through a single mixer from mL/min to L/h.
1. Max flow rate
2. Use with
3. Dilution
Overview
- Accelerated timelines – Simplified workflows and comprehensive technical support expedite drug development and data generation
- Reproducible – Automated and advanced NxGen™ mixing technology minimizes batch-to-batch and user variability to reproducibly generate homogenous particles
- Easy to use – Simple workflows and intuitive software allow users to be up and running quickly
- Minimized risk – The robust design of the system greatly reduces the chances of contamination and user errors, minimizing troubleshooting and downtime
- Controlled assembly – Precise control over fluid flow rates and ratios allows fine-tuning of the critical quality attributes (CQAs), including particle size, to your specifications
- Scalable – The system enables modeling of clinically relevant parameters and processes at small volumes to predictably scale optimized formulations on the NanoAssemblr™ Blaze system and NanoAssemblr™ commercial formulation system
All cartridges are validated for single use only. Beginning in September 2025, customers can request a software upgrade that allows optional reuse of current NxGen™ and NxGen™ 500 cartridges. For advanced applications, the new NxGen™ scale-ready cartridge (coming soon) is a gamma-irradiated version of the NxGen™ 500 cartridge, designed with GMP in mind and optimized to minimize risks in early-phase and small-scale clinical trials. Click here to request a software upgrade to enable reusability and/or learn more about the new NxGen™ scale-ready cartridge.
The NanoAssemblr™ Ignite and Ignite+ systems enable scalable, reproducible, and easy-to-use formulation of lipid nanoparticles (LNP) for preclinical genomic medicine development.
The NanoAssemblr™ Ignite system formulates at the bench scale with volumes of up to 20 mL and flow rates of up to 20 mL/min.
The NanoAssemblr™ Ignite+ system builds on these features with expanded capabilities, formulating up to 60 mL at up to 200 mL/min. This flexibility supports small-scale de-risking of large-scale systems and initiates process development activities using simple, low-volume workflows.
